- Title
- A pharmacological approach to first aid treatment for snakebite
- Creator
- Saul, Megan E.; Thomas, Paul A.; Dosen, Peter J.; Isbister, Geoffrey K.; O'Leary, Margaret A.; Whyte, Ian M.; McFadden, Sally A.; van Helden, Dirk F.
- Relation
- Nature Medicine Vol. 17, Issue 7, p. 809-811
- Publisher Link
- http://dx.doi.org/10.1038/nm.2382
- Publisher
- Nature Publishing Group
- Resource Type
- journal article
- Date
- 2011
- Description
- Snake venom toxins first transit the lymphatic system before entering the bloodstream. Ointment containing a nitric oxide donor, which impedes the intrinsic lymphatic pump, prolonged lymph transit time in rats and humans and also increased rat survival time after injection of venom. This pharmacological approach should give snakebite victims more time to obtain medical care and antivenom treatment.
- Subject
- snake venom; snake bites; lymphatic system; first aid; nitric oxide
- Identifier
- http://hdl.handle.net/1959.13/1044809
- Identifier
- uon:14381
- Identifier
- ISSN:1078-8956
- Language
- eng
- Full Text
- Reviewed
- Hits: 4720
- Visitors: 5208
- Downloads: 851
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Author final version | 315 KB | Adobe Acrobat PDF | View Details Download |